godef

 

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Function

Find GO ontology terms by definition

Description

godef searches the definition of gene ontology terms and returns matching terms. The input is read from the installed GO database. The ontology term output can be written to screen, to file, or passed to another program. A wide range of standard ontology term formats may be specified for input and output.

Optionally the search can be restricted to specified GO namespaces.

Usage

Here is a sample session with godef


% godef glycoprotein 
Find GO ontology terms by definition
Obo output file [godef.obo]: 

Go to the output files for this example

Command line arguments

Find GO ontology terms by definition
Version: EMBOSS:6.4.0.0

   Standard (Mandatory) qualifiers:
  [-query]             string     Definition word(s) to search for in ontology
                                  (Any string)
  [-outfile]           outobo     [*.godef] Output ontology term file name

   Additional (Optional) qualifiers:
   -namespace          menu       [*] By default all terms are returned.
                                  Searches can be limited to one or a few
                                  namespaces. (Values: biological_process
                                  (Biological process); cellular_component
                                  (Cellular component); molecular_function
                                  (Molecular function))

   Advanced (Unprompted) qualifiers:
   -subclasses         boolean    [N] Extend the query matches to include all
                                  terms which are specialisations (GO
                                  sub-classes) of the matched type.
   -obsolete           boolean    [N] The default behaviour is to not use or
                                  return obsolete terms. This option if set
                                  will include all terms.

   Associated qualifiers:

   "-outfile" associated qualifiers
   -odirectory2        string     Output directory
   -oformat2           string     Ontology term output format

   General qualifiers:
   -auto               boolean    Turn off prompts
   -stdout             boolean    Write first file to standard output
   -filter             boolean    Read first file from standard input, write
                                  first file to standard output
   -options            boolean    Prompt for standard and additional values
   -debug              boolean    Write debug output to program.dbg
   -verbose            boolean    Report some/full command line options
   -help               boolean    Report command line options and exit. More
                                  information on associated and general
                                  qualifiers can be found with -help -verbose
   -warning            boolean    Report warnings
   -error              boolean    Report errors
   -fatal              boolean    Report fatal errors
   -die                boolean    Report dying program messages
   -version            boolean    Report version number and exit

Qualifier Type Description Allowed values Default
Standard (Mandatory) qualifiers
[-query]
(Parameter 1)
string Definition word(s) to search for in ontology Any string  
[-outfile]
(Parameter 2)
outobo Output ontology term file name OBO ontology term(s) <*>.godef
Additional (Optional) qualifiers
-namespace list By default all terms are returned. Searches can be limited to one or a few namespaces.
biological_process (Biological process)
cellular_component (Cellular component)
molecular_function (Molecular function)
*
Advanced (Unprompted) qualifiers
-subclasses boolean Extend the query matches to include all terms which are specialisations (GO sub-classes) of the matched type. Boolean value Yes/No No
-obsolete boolean The default behaviour is to not use or return obsolete terms. This option if set will include all terms. Boolean value Yes/No No
Associated qualifiers
"-outfile" associated outobo qualifiers
-odirectory2
-odirectory_outfile
string Output directory Any string  
-oformat2
-oformat_outfile
string Ontology term output format Any string  
General qualifiers
-auto boolean Turn off prompts Boolean value Yes/No N
-stdout boolean Write first file to standard output Boolean value Yes/No N
-filter boolean Read first file from standard input, write first file to standard output Boolean value Yes/No N
-options boolean Prompt for standard and additional values Boolean value Yes/No N
-debug boolean Write debug output to program.dbg Boolean value Yes/No N
-verbose boolean Report some/full command line options Boolean value Yes/No Y
-help boolean Report command line options and exit. More information on associated and general qualifiers can be found with -help -verbose Boolean value Yes/No N
-warning boolean Report warnings Boolean value Yes/No Y
-error boolean Report errors Boolean value Yes/No Y
-fatal boolean Report fatal errors Boolean value Yes/No Y
-die boolean Report dying program messages Boolean value Yes/No Y
-version boolean Report version number and exit Boolean value Yes/No N

Input file format

godef queries the gene ontology.

Output file format

The output is a standard EMBOSS ontology term file.

The results can be output in one of several styles by using the command-line qualifier -oformat xxx, where 'xxx' is replaced by the name of the required format. The available format names are: obo, brief, list, html, xml, json, excel.

See: http://emboss.sf.net/docs/themes/OntologyFormats.html for further information on ontology formats.

Output files for usage example

File: godef.obo

[Term]
id: GO:0004579
name: dolichyl-diphosphooligosaccharide-protein glycotransferase activity
namespace: molecular_function
def: Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine.
synonym: "asparagine N-glycosyltransferase activity" EXACT [EC:2.4.1.119]
synonym: "dolichyl-diphosphooligosaccharide-protein glycosyltransferase activity" EXACT []
synonym: "dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase activity" EXACT [EC:2.4.1.119]
synonym: "dolichyldiphosphooligosaccharide-protein glycosyltransferase activity" EXACT [EC:2.4.1.119]
synonym: "dolichyldiphosphooligosaccharide-protein oligosaccharyltransferase activity" EXACT [EC:2.4.1.119]
synonym: "dolichyldiphosphoryloligosaccharide-protein oligosaccharyltransferase activity" EXACT [EC:2.4.1.119]
synonym: "dolichylpyrophosphodiacetylchitobiose-protein glycosyltransferase activity" EXACT [EC:2.4.1.119]
synonym: "oligomannosyltransferase activity" RELATED [EC:2.4.1.119]
xref: EC:2.4.1.119
xref: MetaCyc:2.4.1.119-RXN
xref: Reactome:12500 "dolichyl-diphosphooligosaccharide-protein glycotransferase activity"
is_a: GO:0004576 ! oligosaccharyl transferase activity

[Term]
id: GO:0015572
name: N-acetylglucosamine transmembrane transporter activity
namespace: molecular_function
def: Catalysis of the transfer of N-acetylglucosamine from one side of the membrane to the other. The D isomer of N-acetylglucosamine is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.
alt_id: GO:0015580
subset: gosubset_prok
synonym: "D-GlcNAc transmembrane transporter activity" EXACT []
synonym: "N-Acetyl-D-glucosamine permease" RELATED []
synonym: "N-acetyl-D-glucosamine transmembrane transporter activity" EXACT []
synonym: "N-acetylchitosamine transmembrane transporter activity" EXACT []
synonym: "N-acetylglucosamine permease activity" RELATED []
is_a: GO:0015149 ! hexose transmembrane transporter activity

[Term]
id: GO:0002162
name: dystroglycan binding
namespace: molecular_function
def: Interacting selectively and non-covalently with dystroglycan. Dystroglycan is glycoprotein found in non-muscle tissues as well as in muscle tissues, often in association with dystrophin. The native dystroglycan cleaved into two non-covalently associated subunits, alpha (N-terminal) and beta (C-terminal).
is_a: GO:0001948 ! glycoprotein binding

[Term]
id: GO:0031150
name: sorocarp stalk development
namespace: biological_process
def: The process whose specific outcome is the progression of the sorocarp stalk over time, from its formation to the mature structure. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum.
synonym: "sorophore development" EXACT []
synonym: "stalk development" BROAD []
synonym: "stalk formation" BROAD []
is_a: GO:0003006 ! developmental process involved in reproduction
is_a: GO:0048856 ! anatomical structure development
relationship: part_of GO:0031154 ! culmination involved in sorocarp development


  [Part of this file has been deleted for brevity]

synonym: "positive regulation of glycoprotein biosynthetic process of formation of immunological synapse" EXACT [GOC:obol]
synonym: "positive regulation of glycoprotein biosynthetic process of immunological synapse formation" EXACT [GOC:obol]
is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process
relationship: part_of GO:0001771 ! immunological synapse formation

[Term]
id: GO:0016914
name: follicle-stimulating hormone complex
namespace: cellular_component
def: A gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland; consists of alpha and beta subunits, the latter of which confers hormonal specificity.
synonym: "follicle stimulating hormone complex" EXACT []
synonym: "FSH complex" EXACT []
is_a: GO:0043234 ! protein complex
is_a: GO:0044421 ! extracellular region part

[Term]
id: GO:0043256
name: laminin complex
namespace: cellular_component
def: A large, extracellular glycoprotein complex composed of three different polypeptide chains, alpha, beta and gamma. Provides an integral part of the structural scaffolding of basement membranes.
subset: goslim_pir
is_a: GO:0043234 ! protein complex
is_a: GO:0044420 ! extracellular matrix part
relationship: part_of GO:0005605 ! basal lamina

[Term]
id: GO:0048829
name: root cap development
namespace: biological_process
def: The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant.
is_a: GO:0048856 ! anatomical structure development
relationship: part_of GO:0048364 ! root development

[Term]
id: GO:0051541
name: elastin metabolic process
namespace: biological_process
def: The chemical reactions and pathways involving elastin, a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.
synonym: "elastin metabolism" EXACT []
is_a: GO:0009100 ! glycoprotein metabolic process

[Term]
id: GO:0033947
name: mannosylglycoprotein endo-beta-mannosidase activity
namespace: molecular_function
def: Catalysis of the hydrolysis of the alpha-D-mannosyl-(1->6)-beta-D-mannosyl-(1->4)-beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequence of glycoprotein to alpha-D-mannosyl-(1->6)-D-mannose and beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequences.
synonym: "endo-beta-mannosidase activity" EXACT [EC:3.2.1.152]
xref: EC:3.2.1.152
xref: MetaCyc:3.2.1.152-RXN
is_a: GO:0015923 ! mannosidase activity

Data files

The gene Ontology is included in EMBOSS as local database go.

Notes

None.

References

None.

Warnings

None.

Diagnostic Error Messages

None.

Exit status

It always exits with status 0.

Known bugs

None.

See also

Program name Description
edamdef Find EDAM ontology terms by definition
edamhasinput Find EDAM ontology terms by has_input relation
edamhasoutput Find EDAM ontology terms by has_output relation
edamisformat Find EDAM ontology terms by is_format_of relation
edamisid Find EDAM ontology terms by is_identifier_of relation
edamname Find EDAM ontology terms by name
goname Find GO ontology terms by name
ontoget Get ontology term(s)
ontogetcommon Get common ancestor for terms
ontogetdown Get ontology term(s) by parent id
ontogetobsolete Get ontology ontology terms
ontogetroot Get ontology root terms by child identifier
ontogetsibs Get ontology term(s) by id with common parent
ontogetup Get ontology term(s) by id of child
ontoisobsolete Report whether an ontology term id is obsolete
ontotext Get ontology term(s) original full text

Author(s)

Peter Rice
European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK

Please report all bugs to the EMBOSS bug team (emboss-bug © emboss.open-bio.org) not to the original author.

History

Target users

This program is intended to be used by everyone and everything, from naive users to embedded scripts.

Comments

None