EMBOSS is used on a very wide variety of computer hardware. Any modern mid-range PC with a typical hardware configuration should be more than adequate. The required disc space depends on the particular platform you are installing on. EMBOSS configured to use shared libraries will require around 100Mb to 200Mb. If you configure it to produce static executables then it may well require three times that amount or more. Of course, you will need additional space for any databases you choose to install.